WebCHIR 99021. Alternative names. CHIR99021. Purity. >98%. Description. Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and … WebSelleck Chemical LLC CHIR-99021 (CT99021) HCl 5mg 1797989-42-4 Manufacturer: Selleck Chemical LLC S29245MG CHIR-99021 (CT99021) HCl is hydrochloride of CHIR-99021, which is a GSK-3α/β inhibitor with …
CHIR-99021 Cell Signaling Technology
WebSupplier: Selleck Chemical LLC S126325MG CHIR-99021 (CT99021) is a GSK-3α and GSK-3β inhibitor with IC50 of 10 nM and 6.7 nM, respectively. CHIR99201 does not exhibit cross-reactivity against cyclin-dependent kinases (CDKs) and shows a 350-fold selectivity toward GSK-3β compared to CDKs. WebLong term media: neural crest maintenance media + 50pg/ml BMP2 (PeproTech, 120-02) + 3uM CHIR-99021 (Selleck Chemicals, S2924) (BCh media). After transition to BCh media, CNCCs at subsequent passages were plated at ~800,000 cells/well of a 6-well plate. CNCCs were then passaged twice to passage 4 where depletion experiments were … ciat biodiversity
CHIR-99021 Cell Signaling Technology
WebCHIR-99021 是一种有效的药理性的 Wnt/beta-catenin 信号通路的激活剂。 CHIR-99021 可显著地拯救光诱导的 autophagy ,并可增强 GR,RORα和自噬相关蛋白等表达。 CAS: 1797989-42-4 客户使用Selleck生产 … WebCHIR-99021, also known as CT-99021, is a potent and selective inhibitor of glycogen synthase kinase-3β (GSK-3β) and GSK-3α with IC 50 values of 6.7 and 10 nM, respectively. This small compound has been shown to … WebSep 28, 2016 · BMDMs were pretreated with GSK-3β specific inhibitor CHIR-99021 or control medium for 12 hours and then exposed to 1, 10 or 100 nM CA1P, respectively. (C) Western blot analysis of p-AKT, p-GSK, β-catenin, and Mcl-1 after Raw 264.7 cells were treated with CA1P for 24 hours. Raw 264.7 cells were also pretreated with CHIR-99021 … dg anchorage\u0027s