WebMay 19, 2015 · DUR-928, an endogenous epigenomic regulator, is an orally bioavailable small molecule that modulates the activity of various nuclear receptors that play an important regulatory role in lipid... WebMar 9, 2024 · DUR-928 is an inhibitor of DNA methyltransferases (DNMTs) regulating expression of genes involved in cell survival, inflammation and lipid biosynthesis Mechanism of action supports development of DUR-928 for the treatment of multiple acute organ injury and chronic diseases Published in peer reviewed Journal of Lipid Research
A 14-Day Intravenous Infusion Toxicity and Toxicokinetic Study of …
WebJan 25, 2024 · DUR-928 epigenetically modulates the expression of multiple clusters of master genes that are involved in many important cell signaling pathways, through which … WebDUR-928, the company's lead drug candidate is in clinical development for the potential treatment of alcohol-associated hepatitis (AH) for which FDA has granted a Fast Track Designation; non-alcoholic steatohepatitis (NASH) is also being explored. ... DUR-928 is an investigational drug candidate under development and has not been approved for . iphone 14 gallery
DURECT Corporation Announces First Patient Dosed in Phase 2b …
WebMar 9, 2024 · DUR-928 is an investigational drug candidate under development and has not been approved for commercialization by the U.S. Food and Drug Administration or other health authorities for any indication. Full prescribing information for POSIMIR, including its Boxed Warning, can be found at www.posimir.com. WebApr 25, 2024 · CUPERTINO, Calif., April 25, 2024 /PRNewswire/ -- DURECT Corporation (Nasdaq: DRRX) today announced it has commenced patient dosing in a Phase 2a ... WebDec 16, 2024 · DUR-928 epigenetically modulates the expression of multiple clusters of master genes that are involved in many important cell signaling pathways, through which … iphone 14 gb sizes